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1.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.304

    Fernandez, P. L.
    Tumours of the mammary gland [Text] / P. L. Fernandez, A. Cardesa, K. Kamino // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P45-58 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли молочной железы
Аннотация: There are very few reports on the experimental induction of tumours of the mammary gland in the hamster. Nevertheless, consideration of the hamster model would seem to be of interest, in view of the fact that the oral administration of 3-methylcholanthrene to this species resulted in the induction of mammary gland carcinomas after short periods of time. In certain aspects, this is a more striking occurrence than in the rat, since spontaneous mammary tumours are exceedingly rare in the hamster, and since in this animal prolonged stimulation with synthetic estrogens did not result in the development of tumours of the breast. Библ. 60
ГРНТИ  
76.29.49
ВИНИТИ 761.29.49.21.07.05 + 761.29.49.25.07
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
МОЛОЧНАЯ ЖЕЛЕЗА
МОРФОЛОГИЯ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
КАНЦЕРОГЕНЫ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Cardesa, A.; Kamino, K.

2.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.305

    Ghadially, F. N.
    Tumors of the skin [Text] / F. N. Ghadially, R. Ghadially // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P1-43 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли кожи
Аннотация: Since the first historic production of tumours of the rabbit skin by Yamagiva & Ishikawa (1918), cancer research workers have extended the study of cutaneous carcinogenesis to a number of other animal species. Cutaneous carcinogenesis has many attractions, perhaps the most important being the fact that the skin provides an opportunity for easy, continuous and accurate observation of its lesions as does no other organ, and that tumours can be raised here not only by a large variety of chemicals but also by various physical and biological agents. Of the animal species recently added to the list of those used for cutaneous carcinogenesis, the hamster stands out as undoubtedly the most important. At least three points set the hamster apart from other species: (1) it has a costovertebral spot in which tumours can be raised by hormonal means; (2) it has small pigmented spots in the skin (comprising networks of melanocytes around some of the hair follicles), from which melanotic tumours can be readily produced; and (3) it has a cheek pouch, which can be exteriorized and used as a glabrous area for carcinogenesis, so that one may compare tumours arising from hairy and non-hairy epithelia. In common with the skin of many laboratory rodents, hamster skin also yields a crop of epithelial and mesenchymal tumours of various types. These include keratoacanthomas, papillomas, squamous cell carcinomas, sebaceous adenomas, basal cell tumours, dermatofibromas and dermatofibrosarcomas. The commonest of the epithelial tumours produced in the skin by chemical carcinogenesis bears a close morphological and behavioural resemblance to the keratoacanthoma of man. Studies of these tumours in rabbit, mouse, hamster, rat, hedgehog, chicken and man have shown that these tumours arise from the hair follicles. The skin with its appendages is a complex dynamic organ, which produces a bewildering variety of tumours. If the histogenesis and behaviour of these tumours is to be understood, one must first recall certain relevant points regarding the biology and morphology of the hair follicles, the small pigmented spots and the costovertebral spots. We shall therefore commence by examining the morphology and function of these structures. Библ. 180
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Рубрики: ОПУХОЛИ СПОНТАННЫЕ
КОЖА
МОРФОЛОГИЯ
ГИСТОЛОГИЯ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Ghadially, R.

3.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.306

    Berman, L. D.
    Tumours of soft tissues [Text] / L. D. Berman // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P321-349 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли мягких тканей
Аннотация: The term `soft tissue' is used here to refer to any of the generalized supporting mesenchymal tissues and includes the following: fibrous, adipose, peripheral, neural, vascular and muscular tissue. The skeletal, central nervous system, lymphoid, synovial and haematological tissues are covered elsewhere. The tumours arise not only in the muscular and subcutaneous tissues, but also in most of the visceral organs where supporting tissue is present. As in the preceding review, the latter types of tumour are only briefly mentioned, since many of them are discussed in the chapters dealing with those visceral organ systems. These tumours are of particular interest due to the unique susceptibility of the hamster to viral oncogenesis. Virtually all major varieties of known oncogenic viruses are tumorigenic in the hamster, and they induce some unique lesions that are not known in any other species. Since most of these tumours are soft-tissue lesions, the hamster provide a singular yardstick for morphological and biological comparison. Библ. 160
ГРНТИ  
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ВИНИТИ 761.29.49.21.07.05 + 761.29.49.25.07
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
МОРФОЛОГИЯ
ОПУХОЛИ МЯГКИХ ТКАНЕЙ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

4.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.307

    Barthold, S. W.
    Tumours of the haematopoietic system [Text] / S. W. Barthold // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P365-383 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли системы гемопоэза
Аннотация: Tumours of the haematopoietic system are an important group of tumours in the hamster. Tumours of lymphoreticular origin are among the most common spontaneous tumours in aged hamsters and appear to be the most frequent malignant neoplasm. Lymphoreticular tumours have also been induced experimentally by a number of means, including X-irradiation, chemical carcinogens, viruses and tissue extracts. Their relatively high rate of occurrence in untreated hamsters has often obscured the significance of their induction by experimental means. These tumours often contain a number of virus-like particles of unknown biological significance. A virus of clear significance is hamster papovavirus, which can cause epizootics or enzootics of transmissible lymphoma. It has confounded a number of hamster experiments, including ones investigating its own pathogenesis. Библ. 94
ГРНТИ  
76.29.49
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Рубрики: ГЕМОБЛАСТОДЫ
ОПУХОЛИ СПОНТАННЫЕ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
КАНЦЕРОГЕНЫ
РЕНТГЕНОВСКОЕ ОБЛУЧЕНИЕ
ВИРУСЫ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

5.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.308

    Schmidt, R. E.
    Tumours of the endocrine glands [Text] / R. E. Schmidt, G. B. Hubbard // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P307-320 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли эндокринных желез
Аннотация: This review is principally concerned with primary tumours of the endocrine glands of various strains of Syrian hamsters. Most of the literature documenting endocrine tumours concerns Syrian hamsters, although endocrine neoplasms in Chinese, European and Dzungarian hamsters have also been described. Adenomas and adenocarcinomas are described in the pituitary, thyroid, parathyroid, adrenal glands and the islets of Langerhans. Библ. 82
ГРНТИ  
76.29.49
ВИНИТИ 761.29.49.21.07.05 + 761.29.49.25.07
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
МОРФОЛОГИЯ
ЭНДОКРИННЫЕ ЖЕЛЕЗЫ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
ХОМЯЧКИ

Доп.точки доступа:
Hubbard, G.B.

6.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.309

    Ribas, J. L.
    Tumours of the female genital system [Text] / J. L. Ribas, J. M. Pletcher // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P281-305 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли женских половых органов
Аннотация: In the area chemical carcinogenesis of the genital system, relatively few agents have been tested in the hamster, and only four have produced a significant yield of tumours. Spontaneous neoplasmas of the reproductive tract of the female hamster are uncommon, although among different colonies the incidence may range from 3.5 to 11% and the pre-dilection site may also vary. When a large number of untreated and estrogen-treated female hamsters in the Stanford colony were compared, the incidence of ovarian tumours in untreated animals was 0.12% as opposed to 0.28% for estrogen-treated ones, while the corresponding figures for uterine tumours were 0.22% and 1.40%. The low incidence of spontaneous genital tumours, coupled with the range of preneoplastic and neoplastic conditions that can be induced by some chemical carcinogens, makes the hamster a potentially valuable biological system for studying etiology and pathogenesis, hormone-dependence, autonomous growth, morphology, biological behaviour and treatment of induced tumours of the female reproductive tract. In addition to reviewing the literature since 1965, this chapter includes comparisons, where possible, of the different tumours of the female reproductive tract of the hamster with their human counterparts. However, the WHO classification of human ovarian and genital tract tumours is complex due to the large numbers of different tumours arising from these organs. In contrast, relatively few spontaneous tumours arise from the genital tract of female hamsters, making a direct comparison between human and hamster neoplasms of limited value. Earlier literature on hamster tumours has been reviewed by various authors. Additional reviews on hormone-induced tumours of the reproductive tract of the female hamster and its transplantable tumours are also available. Библ. 140
ГРНТИ  
76.29.49
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Рубрики: ОПУХОЛИ СПОНТАННЫЕ
ОПУХОЛИ ЖЕНСКИХ ПОЛОВЫХ ОРГАНОВ
МОРФОЛОГИЯ
ГИСТОЛОГИЯ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Pletcher, J.M.

7.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.313

    Ribas, J. L.
    Tumours of the testis and accessory male sex glands [Text] / J. L. Ribas, F. K. Mostofi // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P261-280 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли яичка и придаточных половых желез у самцов
Аннотация: Despite extensive study of the hamster, spontaneous tumours of the testis and accessory sex glands have rarely been reported. In part, this may be due to the fact that in the laboratory hamster, as in other mammalian species, the incidence of neoplasia increases with advancing age but the life of an experimental animal is shortened by design. It may also reflect a lack of thoroughness in some pathological studies, particularly since many tumours cannot be detected grossly; some workers have attributed higher tumour incidences in their studies to the intensive histological examination of step sections in multiple organs. This review provides an update of the review by Kirkman and Kempson in the first edition of this volume. It also compares the hamster tumours, when possible, to their human counterparts, according to classifications based on the WHO Histological Typing of Testis Tumours and of Prostate Tumours. It should be noted that the literature in this area is fragmentary and widely scattered, and it is occasionally anecdotal or buried in technical reports which are not usually included in standard bibliographic data-bases. More importantly, there has been a lack of uniformity in histological diagnosis in the literature. Библ. 164
ГРНТИ  
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Рубрики: ОПУХОЛИ СПОНТАННЫЕ
ОПУХОЛИ ЯИЧКА
МОРФОЛОГИЯ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Mostofi, F.K.

8.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.314

    Pour, P. M.
    Tumors of the bone [Text] / P. M. Pour // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P385-426 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли костей
Аннотация: The Syrian golden hamster (Cricetus auratus) has not been used extensively for studies of experimental induction of bone tumours. Therefore, in comparison with other laboratory rodents, less is known of the development, anatomy and spontaneous diseases of its skeleton. However, this species provides a suitable model for comparative studies, of not only skeletal but also odontogenic diseases, because some spontaneous and induced lesions of the bone, supporting tissues and dental structures resemble morphologically those occurring in humans. The etiology of bone tumours (including dental neoplasms) in humans is unknown and a practical experimental model could provide information about the factors involved in the pathogenesis of skeletal and dental neoplasms. Библ. 172
ГРНТИ  
76.29.49
ВИНИТИ 761.29.49.21.07.05 + 761.29.49.25.07
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
ОПУХОЛИ КОСТЕЙ
МОРФОЛОГИЯ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

9.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.315

   
    Tumours of the kidney [Text] / H. Tsuda [et al.] // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P223-242 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли почек
Аннотация: Naturally occurring kidney tumours are uncommon in rodents, including the Syrian golden hamster. This is in contrast to the relatively high yields of spontaneous liver, mammary or lung tumours seen in certain strains of rats and mice. However, the kidney of various species is susceptible to a variety of carcinogenic insults, either chemical or viral, and the hamster is no exception. Indeed, apart from the generally nitrosamine-induced tubular lesions shared in common with other rodents, the Syrian golden hamster is unique in responding to estrogenic stimulus by development of hormonedependent kidney tumours of uncertain origin. Библ. 260
ГРНТИ  
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ВИНИТИ 761.29.49.21.07.05 + 761.29.49.25.07
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
ОПУХОЛИ ПОЧЕК
МОРФОЛОГИЯ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Tsuda, H.; Kim, D.J.; Kato, T.; Hakoi, K.; Hagiwara, A.

10.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.317

    Pour, P. M.
    Tumours of the pancreas [Text] / P. M. Pour, T. Tomioka // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P149-173 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли поджелудочной железы
ГРНТИ  
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Рубрики: ОПУХОЛИ СПОНТАННЫЕ
РАК ПОДЖЕЛУДОЧНОЙ ЖЕЛЕЗЫ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МОРФОЛОГИЯ
ГИСТОЛОГИЯ
МЕТОДЫ ИНДУКЦИИ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Tomioka, T.

11.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.318

    Turusov, V. S.
    Tumours of the gallbladder [Text] / V. S. Turusov, B. Gorin // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P109-125 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли мочевого пузыря
ГРНТИ  
76.29.49
ВИНИТИ 761.29.49.21.07.05 + 761.29.49.25.07
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
МОЧЕВОЙ ПУЗЫРЬ
МОРФОЛОГИЯ
МЕТАСТАЗЫ
ОПУХОЛИ ИНДУЦИРОВАННЫЕ
МЕТОДЫ ИНДУКЦИИ
КАНЦЕРОГЕНЫ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Gorin, B.

12.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.439

   
    Tumours of the nervous system [Text] / A. Cardesa [et al.] // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P427-465 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли нервной системы
Аннотация: Advances in viral and chemical carcinogenesis have led to the development of new experimental approaches, resulting in the induction of a wide range of tumours of the nervous system. The intracerebral injection of oncogenic viruses into newborn animals and the transplacental administration of resorptive chemical carcinogens capable of crossing both the placental and haematoencephalic barriers resulted in the induction of the first types of neurogenic tumours in hamsters. The considerable variety of tumours of nervous origin that have since been produced in the hamster, in contrast to the almost complete absence of spontaneous tumours, makes this animal species a useful biological system for studying the etiology, pathogenesis, morphology, biological behaviour and treatment of tumours of the central and peripheral nervous system. This is of interest since primary tumours of the central nervous system account for approximately 9% of all primary neoplasms in humans. Since the first edition of this review was compiled the following new types of tumours of the nervous system have been experimentally induced in the hamster and are therefore described below: pinealocytoma, gliomatosis cerebri, medullo-epithelioma, ependymoblastoma, primitive polar spongioblastoma, neuroblastoma (central and peripheral), ganglioneuroblastoma, plexiform neurofibroma, esthesioneuroblastoma and retinoblastoma. Библ. 180
ГРНТИ  
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ВИНИТИ 761.29.49.25.07 + 761.29.49.21.07.05
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
ОПУХОЛИ НЕРВНОЙ СИСТЕМЫ
МОРФОЛОГИЯ
ГИСТОЛОГИЯ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Cardesa, A.; ZuRhein, G.M.; Cruz-Sanchez, F.F.; Turusov, V.S.

13.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.440

    Takahashi, M.
    Tumours of the intestine [Text] / M. Takahashi, H. Okamiya // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P137-147 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли тонкой кишки
Аннотация: Intestinal cancer can be induced in rats, mice and hamsters by indirect-acting chemical carcinogens related to either 3,2-dimethyl-4-aminobiphenyl (DMAB) or 1,2-dimethylhydrazine (DMH). Such experimental studies have aroused considerable interest because of their potential relevance to the role of environmental carcinogens and co-carcinogens in the pathogenesis of human bowel cancer. Most studies have, however, used rats and mice, and only a few reports have been published concerning hamsters. Библ. 60
ГРНТИ  
76.29.49
ВИНИТИ 761.29.49.25.07 + 761.29.49.21.07.05
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
ОПУХОЛИ ТОНКОЙ КИШКИ
МОРФОЛОГИЯ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
КАНЦЕРОГЕНЫ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Okamiya, H.

14.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.441

    Takahashi, M.
    Tumours of the glandular stomach [Text] / M. Takahashi, H. Okamiya // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P127-135 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли железистого желудка
Аннотация: Although suitable animal models for the induction of adenocarcinoma in the glandu-lar stomachs of rats and dogs with N-methyl-N-nitro-N-nitrosoguanidine (MNNG) are well established, experimental production of tumours in the glandular stomach of hamsters has been only rarely reported. One reason is the complication of high sarcoma incidences. Библ. 9
ГРНТИ  
76.29.49
ВИНИТИ 761.29.49.25.07 + 761.29.49.21.07.05
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
ЖЕЛЕЗИСТЫЙ ЖЕЛУДОК
МОРФОЛОГИЯ
ГИСТОЛОГИЯ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
КАНЦЕРОГЕНЫ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Okamiya, H.

15.
РЖ ВИНИТИ 76 (BI29) 97.11-04Н1.442

    Moore, M. A.
    Tumours of the liver [Text] / M. A. Moore, W. Thamavit, P. Bannasch // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P79-108 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли печени
Аннотация: The liver of the hamster demonstrates a wide range of morphological and biochemical alterations in response to chemical and physical insult. Some are clearly the result of acute toxicity of chemical agents or in some cases physical damage, while others are unequivocally members of the classes of tumours and their pre-stages which can arise in this organ. There are morphological entities, however, which are less easy to categorize, such as proliferative changes involving hepatocytes and ductular cells which require particular diagnostic care. The present review attempts to clarify the relationships between morphological changes encountered in histopathological investigation of the hamster liver, as well as focusing attention on comparability with lesions arising in other rodents and man. Библ. 150
ГРНТИ  
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ВИНИТИ 761.29.49.25.07 + 761.29.49.21.07.05
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
ОПУХОЛИ ПЕЧЕНИ
МОРФОЛОГИЯ
ГИСТОЛОГИЯ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
КАНЦЕРОГЕНЫ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Thamavit, W.; Bannasch, P.

16.
РЖ ВИНИТИ 76 (BI40) 97.11-04М7.33

    Pour, P. M.
    Tumours of the pancreas [Text] / P. M. Pour, T. Tomioka // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P149-173 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли поджелудочной железы
ГРНТИ  
76.03.49
ВИНИТИ 761.03.49.01.29
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
РАК ПОДЖЕЛУДОЧНОЙ ЖЕЛЕЗЫ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МОРФОЛОГИЯ
ГИСТОЛОГИЯ
МЕТОДЫ ИНДУКЦИИ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Tomioka, T.

17.
РЖ ВИНИТИ 76 (BI40) 97.11-04М7.289

    Fernandez, P. L.
    Tumours of the mammary gland [Text] / P. L. Fernandez, A. Cardesa, K. Kamino // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P45-58 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли молочной железы
Аннотация: There are very few reports on the experimental induction of tumours of the mammary gland in the hamster. Nevertheless, consideration of the hamster model would seem to be of interest, in view of the fact that the oral administration of 3-methylcholanthrene to this species resulted in the induction of mammary gland carcinomas after short periods of time. In certain aspects, this is a more striking occurrence than in the rat, since spontaneous mammary tumours are exceedingly rare in the hamster, and since in this animal prolonged stimulation with synthetic estrogens did not result in the development of tumours of the breast. Библ. 60
ГРНТИ  
76.03.49
ВИНИТИ 761.03.49.43.25.19
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
МОЛОЧНАЯ ЖЕЛЕЗА
МОРФОЛОГИЯ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
КАНЦЕРОГЕНЫ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Cardesa, A.; Kamino, K.

18.
РЖ ВИНИТИ 76 (BI40) 97.11-04М7.308

    Ghadially, F. N.
    Tumors of the skin [Text] / F. N. Ghadially, R. Ghadially // Pathol. Tumours Lab. Anim. - Lyon, 1996. - Vol. 3. - P1-43 . - ISBN 92-832-2126-5
Перевод заглавия: Опухоли кожи
Аннотация: Since the first historic production of tumours of the rabbit skin by Yamagiva & Ishikawa (1918), cancer research workers have extended the study of cutaneous carcinogenesis to a number of other animal species. Cutaneous carcinogenesis has many attractions, perhaps the most important being the fact that the skin provides an opportunity for easy, continuous and accurate observation of its lesions as does no other organ, and that tumours can be raised here not only by a large variety of chemicals but also by various physical and biological agents. Of the animal species recently added to the list of those used for cutaneous carcinogenesis, the hamster stands out as undoubtedly the most important. At least three points set the hamster apart from other species: (1) it has a costovertebral spot in which tumours can be raised by hormonal means; (2) it has small pigmented spots in the skin (comprising networks of melanocytes around some of the hair follicles), from which melanotic tumours can be readily produced; and (3) it has a cheek pouch, which can be exteriorized and used as a glabrous area for carcinogenesis, so that one may compare tumours arising from hairy and non-hairy epithelia. In common with the skin of many laboratory rodents, hamster skin also yields a crop of epithelial and mesenchymal tumours of various types. These include keratoacanthomas, papillomas, squamous cell carcinomas, sebaceous adenomas, basal cell tumours, dermatofibromas and dermatofibrosarcomas. The commonest of the epithelial tumours produced in the skin by chemical carcinogenesis bears a close morphological and behavioural resemblance to the keratoacanthoma of man. Studies of these tumours in rabbit, mouse, hamster, rat, hedgehog, chicken and man have shown that these tumours arise from the hair follicles. The skin with its appendages is a complex dynamic organ, which produces a bewildering variety of tumours. If the histogenesis and behaviour of these tumours is to be understood, one must first recall certain relevant points regarding the biology and morphology of the hair follicles, the small pigmented spots and the costovertebral spots. We shall therefore commence by examining the morphology and function of these structures. Библ. 180
ГРНТИ  
76.03.49
ВИНИТИ 761.03.49.47.19
Рубрики: ОПУХОЛИ СПОНТАННЫЕ
КОЖА
МОРФОЛОГИЯ
ГИСТОЛОГИЯ
ОПУХОЛИ ЭКСПЕРИМЕНТАЛЬНЫЕ
МЕТОДЫ ИНДУКЦИИ
ЛАБОРАТОРНЫЕ ЖИВОТНЫЕ

Доп.точки доступа:
Ghadially, R.

19.
Патент 5939267 Соединенные Штаты Америки, МКИ C12Q 1/68.

    Maiese, Kenneth.
    Methods for the temporal analysis of programmed cell death in living cells [Текст] / Kenneth Maiese, Andrea M. Vincent ; Wayne State University. - № 09/144045 ; Заявл. 31.08.1998 ; Опубл. 17.08.1999
Перевод заглавия: Методы для анализа запрограммированной клеточной смерти во времени в живых клетках
Аннотация: Предложены методы индукции запрограммированной клеточной смерти (ЗКС) и ее анализ во времени. Методы позволяют рассматривать различные ступени ЗКС на микроскопическом препарате по окраске клеток. Используют определение аннексина V и метку для остатков фосфатидилсерина, к-рые могут быть представлены на поверхности живых клеток. Т. обр. описан уникальных способ возможности отслеживания в живых клетках ранних стадий ЗКС. Подчеркивают, что окрашивание аннексина V флуоресцентными соединениями происходит быстро, этот процесс обратим и минимально разрушает клетки
ГРНТИ  
34.19.19
ВИНИТИ 341.19.19.23
Рубрики: АПОПТОЗ
МОДЕЛИРОВАНИЕ
МЕТОДЫ ИНДУКЦИИ
АНАЛИЗ ВО ВРЕМЕНИ
АННЕКСИН V
ПРИЖИЗНЕННЫЕ ИССЛЕДОВАНИЯ

Доп.точки доступа:
Vincent, Andrea M.; Wayne State University
Свободных экз. нет
20.
Патент 5945576 Соединенные Штаты Америки, МКИ C12N 5/00.

    Parker, Christina M.
    Mouse model of psoriasis [Текст] / Christina M. Parker, Michael P. Schon ; Brigham & Women'n Hospital, Inc. - № 08/628761 ; Заявл. 05.04.1996 ; Опубл. 31.08.1999
Перевод заглавия: Модель псориаза у мышей
Аннотация: Предложен метод и вещества для индукции псориаза у мышей. Метод включает введение лимфоцитов донора реципиентам - иммунодефицитным мышам с целью индукции у них кожных воспалений. Мышиная модель применима для подбора и оценки лечебного эффекта антипсориатических препаратов. Библ. 29
ГРНТИ  
34.43.55
ВИНИТИ 341.43.55.29
Рубрики: ПСОРИАЗ
ЭКСПЕРИМЕНТАЛЬНАЯ МОДЕЛЬ
МЕТОДЫ ИНДУКЦИИ
ПРОВЕРКА АНТИПСОРИАТИЧЕСКИХ ПРЕПАРАТОВ
МЫШИ
ПАТЕНТ США

Доп.точки доступа:
Schon, Michael P.; Brigham & Women'n Hospital; Inc.
Свободных экз. нет
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