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РЖ ВИНИТИ 34 (BI24) 95.12-04М3.335

Pfleger, Bruce.
Dynamic differentiation of GABA[A]-sensitive influences on orientation selectivity of complex cells in the cat striate cortex [Text] / Bruce Pfleger, A. B. Bonds // Exp. Brain Res. - 1995. - Vol. 104, N 1. - P81-88 . - ISSN 0014-4819
Перевод заглавия: Динамическая дифференциация ГАМК[A]-чувствительных влияний на ориентационную избирательность сложных нейронов стриарной коры кошки
Аннотация: The influence of GABA[A] receptors on orientation selectivity of cat complex cells was tested by iontophoresis of the GABA[A] receptor blockers bicuculline and N-methyl-bicuculline while stimulating with drifting sinusoidal gratings. Reduction of orientation tuning was markedly less than reported in previous studies that used drifting bars as visual stimuli. Only 3/31 cells lost orientation selectivity, with an average increase in bandwidth of 33%, as opposed to half the cells losing selectivity and a bandwidth increase for the remainder of 47% as reported previously. Infusion of GABA[A] blockers revealed a prominent stimulus onset transient response, lasting about 120 ms, that showed a broadening of orientation selectivity comparable to that found using drifting bars under similar circumstances. The authors believe that drifting gratings emphasize a steady-state response component that retains, in the presence of GABA[A] blockers, significant orientation selectivity. Because the onset transient is initially inselective for orientation, we suggest that the steady-state, orientation-selective response component develops from an alternate inhibitory mechanism, possibly mediated by GABA[B] receptors. Библ. 46

ГРНТИ	34.39.19

ВИНИТИ 341.39.19.09.15
Рубрики: ЗРИТЕЛЬНАЯ КОРА
ФАЗИЧЕСКИЕ РЕАКЦИИ
ОРИЕНТАЦИОННАЯ ИЗБИРАТЕЛЬНОСТЬ
ГАМК
БИКУКУЛЛИН
КОШКИ

Доп.точки доступа:
Bonds, A.B.

РЖ ВИНИТИ 34 (BI05) 96.02-04И8.199

Pfleger, Bruce.
Dynamic differentiation of GABA[A]-sensitive influences on orientation selectivity of complex cells in the cat striate cortex [Text] / Bruce Pfleger, A. B. Bonds // Exp. Brain Res. - 1995. - Vol. 104, N 1. - P81-88 . - ISSN 0014-4819
Перевод заглавия: Динамическая дифференциация ГАМК[A]-чувствительных влияний на ориентационную избирательность сложных нейронов стриарной коры кошки
Аннотация: The influence of GABA[A] receptors on orientation selectivity of cat complex cells was tested by iontophoresis of the GABA[A] receptor blockers bicuculline and N-methyl-bicuculline while stimulating with drifting sinusoidal gratings. Reduction of orientation tuning was markedly less than reported in previous studies that used drifting bars as visual stimuli. Only 3/31 cells lost orientation selectivity, with an average increase in bandwidth of 33%, as opposed to half the cells losing selectivity and a bandwidth increase for the remainder of 47% as reported previously. Infusion of GABA[A] blockers revealed a prominent stimulus onset transient response, lasting about 120 ms, that showed a broadening of orientation selectivity comparable to that found using drifting bars under similar circumstances. The authors believe that drifting gratings emphasize a steady-state response component that retains, in the presence of GABA[A] blockers, significant orientation selectivity. Because the onset transient is initially inselective for orientation, we suggest that the steady-state, orientation-selective response component develops from an alternate inhibitory mechanism, possibly mediated by GABA[B] receptors. Библ. 46

ГРНТИ	34.39.57

ВИНИТИ 341.39.57.69
Рубрики: ЗРИТЕЛЬНАЯ КОРА
ФАЗИЧЕСКИЕ РЕАКЦИИ
ОРИЕНТАЦИОННАЯ ИЗБИРАТЕЛЬНОСТЬ
ГАМК
БИКУКУЛЛИН
КОШКИ

Доп.точки доступа:
Bonds, A.B.

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