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РЖ ВИНИТИ 76 (BI40) 96.07-04М7.44

Экспрессия факторов CD116, CD15 и CD-35 человеческих гранулоцитов, стимулированных экстрактом листьев бамбука [Text] / Tsuyoshi Onogawa [et al.] // Kyorin igakkai zasshi = J. Kyorin Med. Soc. - 1995. - Vol. 26, N 2. - С. 165-171 . - ISSN 0368-5829
Аннотация: We have examined whether CD11b, CD15 and CD35 on human granulocytes as adhesion molecules, related to both rolling along and attachment to endothelium, were increased by treatment with bamboo-leaf extract (BE), in vitro. The amount of each adhesion molecule on these cells was measured by flow cytometry and was represented as fluorescence intensities. The fluorescence intensities of CD11b, CD15 and CD35 on cells treated with Fr. -a or Fr. -b showed about twofold increase compared to untreatment cells. The Fr. -a and Fr. -b concentrations at which the value of these adhesion molecules reached a maximum flurorescence intensity were as followed: CD11b, 0.067 mg/ml and 0.33 mg/ml; CD15, 0.33 mg/ml and 2.0 mg/ml; CD35, 0.013 mg/ml and 0.067 mg/ml, respectively. CD35 positive granulocytes by treatment with low concentration (0.013 mg/ml and 0.067 mg/ml) of Fr. -a or Fr. -b increased about 12 per cent compared to untreatment cells. These results suggest that human granulocytes were stimulatd directly or indirectly by BE, in vitro and were induced by BE the expressions of adhesion molecules on the cells. Япония, Kyorin Univ. School of Health Sci. Библ. 21

ГРНТИ	76.03.49

ВИНИТИ 761.03.49.02.05.23
Рубрики: ГИСТОЛОГИЯ
ГРАНУЛОЦИТЫ
ЭКСТРАКТ БАМБУКА
ЭКСПРЕССИЯ ФАКТОРОВ
ИММУНОГИСТОХИМИЯ
ЧЕЛОВЕК

Доп.точки доступа:
Onogawa, Tsuyoshi; Okuda, Toshirou; Endo, Nobuko; Kanamori, Masato

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