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РЖ ВИНИТИ 34 (BI23) 96.10-04М2.242

Jones, James F. X.
Heart rate responses to selective stimulation of cardiac vagal C fibres in anaesthetized cats, rats and rabbits [Text] / James F. X. Jones, Yun Wang, David Jordan // J. Physiol. - 1995. - Vol. 489, N 1. - P203-214 . - ISSN 0022-3751
Перевод заглавия: Реакция частоты сердечных сокращений на селективную стимуляцию сердечных вагусных C волокон у наркотизированных кошек, крыс и кроликов
Аннотация: After bilateral vagotomy and pretreatment with atonolol, 10 Hz continuous selective stimulation of unmyelinated fibres in the cut peripheral end of the cervical vagus evoked a bradycardia in anaesthetized rats, cats and rabbits. With this stimulation protocol the three species exhibited a similar lengthening of the heart period (R-R interval) when expressed as a percentage of their basal cardiac interval. The mechanism of action of the selective blocking technique was analysed by recording eighty-nine single A-(n=12), B-(n=22) and C-fibre (n=55) vagal-projecting neurones in the medulla of the rat. This demonstrated that the technique can selectively block conduction in myelinated fibres and that `break excitation' is seen mainly in unmyelinated fibres. Although thirty C fibres showed break excitation sixteen did not and this difference could not be correlated with their axonal conduction velocity, chronaxie or initial segment frequency following. In conclusion, in addition to the well-defined effects of vagal B fibres on heart rate, selective stimulation of vagal C fibres also had a cardioinhibitory effect in all three species studied. Библ. 29

ГРНТИ	34.39.29

ВИНИТИ 341.39.29.11.09
Рубрики: СЕРДЦЕ
ЧАСТОТА СОКРАЩЕНИЙ
БЛУЖДАЮЩИЙ НЕРВ (X)
ВОЛОКНА* C-
КОШКИ
КРЫСЫ
КРОЛИКИ

Доп.точки доступа:
Wang, Yun; Jordan, David

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