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Общее количество найденных документов : 28
Показаны документы с 1 по 20
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1.
| Indoles and pyridazino[4,5-b]indoles as nonnucleoside analog inhibitors of HIV-1 reverse transcriptase // Eur. J. Med. Chem., 1995. Vol. 30, N 12.-С.963-971
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2.
| Novel oxazolo[3',2':1,2]pyrrolo[3,4-d]pyridazines and imidazolo[1',2':1,2]pyrrolo[3,4-d]pyridazines: Synthesis and biological evaluation // Arch. Pharm., 1996. Vol. 329, N 8-9.-С.403-407
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3.
| Biological evaluation of selected plants from Poland // Int. J. Pharmacognosy, 1997. Vol. 35, N 1.-С.1-5
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4.
| Biological evaluation of selected plants from Poland // Int. J. Pharmacognosy, 1997. Vol. 35, N 1.-С.1-5
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5.
| Flavanone and flavonol glycosides from the leaves of Thevetia peruviana and their HIV-1 reverse transcriptase and HIV-1 integrase inhibitory activities // Chem. and Pharm. Bull., 2002. Vol. 50, N 5.-С.630-635
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6.
| Flavanone and flavonol glycosides from the leaves of Thevetia peruviana and their HIV-1 reverse transcriptase and HIV-1 integrase inhibitory activities // Chem. and Pharm. Bull., 2002. Vol. 50, N 5.-С.630-635
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7.
| Substrate requirements for secondary cleavage by HIV-1 reverse transcriptase RNase H // J. Biol. Chem., 2002. Vol. 277, N 32.-С.28400-28410
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| Mutations E44D and V118I in the reverse transcriptase of HIV-1 play distinct mechanistic roles in dual resistance to AZT and 3TC // J. Biol. Chem., 2003. Vol. 278, N 36.-С.34403-34410
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| The Y181C substitution in 3'azido-3'-deoxythymidine-resistant human immunodeficiency virus, type 1, reverse transcriptase suppresses the ATP-mediated repair of the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer // J. Biol. Chem., 2003. Vol. 278, N 42.-С.40464-40472
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10.
| Kinetic evidence for interaction of human immunodeficiency virus type 1 reverse transcriptase with the 3'-OH of the incoming dTTP substrate // Biochemistry, 2005. Vol. 44, N 31.-С.10635-10643
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11.
| Lanciault Single unpaired nucleotides facilitate HIV-1 reverse transcriptase displacement synthesis through duplex RNA // J. Biol. Chem., 2004. Vol. 279, N 31.-С.32252-32261
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12.
| Geitmann Biosensor-based kinetic characterization of the interaction between HIV-1 reverse transcriptase and non-nucleoside inhibitors // J. Med. Chem., 2006. Vol. 49, N 8.-С.2367-2374
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| Geitmann Interaction kinetic characterization of HIV-1 reverse transcriptase non-nucleoside inhibitor resistance // J. Med. Chem., 2006. Vol. 49, N 8.-С.2375-2387
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14.
| Geitmann Biosensor-based kinetic characterization of the interaction between HIV-1 reverse transcriptase and non-nucleoside inhibitors // J. Med. Chem., 2006. Vol. 49, N 8.-С.2367-2374
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15.
| Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors // Proc. Nat. Acad. Sci. USA, 2004. Vol. 101, N 29.-С.10548-10553
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16.
| Structure-activity relationships of [2',5'-bis-O-(tert-butyldimethylsilyl)-'бета'-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine derivatives as inhibitors of HIV-1 reverse transcriptase dimerization // J. Med. Chem., 2006. Vol. 49, N 16.-С.4834-4841
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17.
| Synthesis and anti-HIV-1 activity evaluation of 5-alkyl-2-alkylthio-6-(arylcarbonyl or 'альфа'-cyanoarylmethyl)-3,4-dihydropyrimidin-4(3H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors // J. Med. Chem., 2007. Vol. 50, N 8.-С.1778-1786
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18.
| Investigating the "steric gate" of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by targeted insertion of unnatural amino acids // Biochemistry, 2007. Vol. 46, N 8.-С.2118-2126
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| Synthesis, biological activity, and crystal structure of potent nonnucleoside inhibitors of HIV-1 reverse transcriptase that retain activity against mutant forms of the enzyme // J. Med. Chem., 2007. Vol. 50, N 17.-С.4003-4015
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20.
| Reduced dNTP binding affinity of 3TC-resistant M184I HIV-1 reverse transcriptase variants responsible for viral infection failure in macrophage // J. Biol. Chem., 2008. Vol. 283, N 14.-С.9206-9216
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