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Общее количество найденных документов : 53
Показаны документы с 1 по 20
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1.
| Uckun Fatih M. NNI for treatment of multi-drug resistant HIV
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| Uckun Fatih M. NNI for treatment of multi-drug resistant HIV
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| Phase 2a randomized controlled trial of short-term activity, safety, and pharmacokinetics of a novel nonnucleoside reverse transcriptase inhibitor, RDEA806, in HIV-1-positive, antiretroviral-naive subjects // Antimicrob. Agents and Chemother., 2010. Vol. 54, N 8.-С.3170-3178
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| Synthesis and anti-HIV-1 activity evaluation of 5-alkyl-2-alkylthio-6-(arylcarbonyl or 'альфа'-cyanoarylmethyl)-3,4-dihydropyrimidin-4(3H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors // J. Med. Chem., 2007. Vol. 50, N 8.-С.1778-1786
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| Substrate-dependent inhibition or stimulation of HIV RNase H activity by non-nucleoside reverse transcriptase inhibitors (NNRTIs) // Biochem. and Biophys. Res. Commun., 2007. Vol. 352, N 2.-С.341-350
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| Hepatitis C virus (HCV) NS5B nonnucleoside inhibitors specifically block single-stranded viral RNA synthesis catalyzed by HCV replication complexes in vitro // Antimicrob. Agents and Chemother., 2007. Vol. 51, N 1.-С.338-342
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| Molecular mechanism of a thumb domain hepatitis C virus nonnucleoside RNA-dependent RNA polymerase inhibitor // Antimicrob. Agents and Chemother., 2006. Vol. 50, N 12.-С.4103-4113
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| High potency of indolyl aryl sulfone nonnucleoside inhibitors towards drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutants is due to selective targeting of different mechanistic forms of the enzyme // Antimicrob. Agents and Chemother., 2005. Vol. 49, N 11.-С.4546-4554
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| A novel nonnucleoside analogue that inhibits human immunodeficiency virus type 1 isolates resistant to current nonnucleoside reverse transcriptase inhibitors // Antimicrob. Agents and Chemother., 2007. Vol. 51, N 2.-С.429-437
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| Molecular mechanism of a thumb domain hepatitis C virus nonnucleoside RNA-dependent RNA polymerase inhibitor // Antimicrob. Agents and Chemother., 2006. Vol. 50, N 12.-С.4103-4113
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11.
| A novel nonnucleoside analogue that inhibits human immunodeficiency virus type 1 isolates resistant to current nonnucleoside reverse transcriptase inhibitors // Antimicrob. Agents and Chemother., 2007. Vol. 51, N 2.-С.429-437
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12.
| High potency of indolyl aryl sulfone nonnucleoside inhibitors towards drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutants is due to selective targeting of different mechanistic forms of the enzyme // Antimicrob. Agents and Chemother., 2005. Vol. 49, N 11.-С.4546-4554
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13.
| High potency of indolyl aryl sulfone nonnucleoside inhibitors towards drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutants is due to selective targeting of different mechanistic forms of the enzyme // Antimicrob. Agents and Chemother., 2005. Vol. 49, N 11.-С.4546-4554
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14.
| Comparative analysis of diverse nonnucleoside rt inhibitors // J. Cell. Biochem., 1994, Suppl. 18В.-С.160
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| Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase I: Tricyclic pyridobenzo-and dipyridodiazepinones // J. Med. Chem., 1991. Vol. 34, N 7.-С.2231-2241
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| Бабков Д.А. СИНТЕЗ 3-[2-(2-БЕНЗОИЛФЕНОКСИ)ЭТИЛ]-1-[2-(ФЕНОКСИ)ЭТИЛ]ПРОИЗВОДНЫХ УРАЦИЛА КАК ПОТЕНЦИАЛЬНЫХ АНТИ-ВИЧ-1 АГЕНТОВ // Фундам. исслед., 2014, N 9.-С.2440-2445
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| Brown Jodian A. Dual allosteric inhibitors jointly modulate structure and dynamics in the Hepatitis C Virus polymerase // J. Biomol. Struct. and Dyn., 2015. Vol. 33, прил..-С.116-117
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| Дизайн новых производных урацила, обладающих ингибиторной активностью в отношении обратной транскриптазы мутанта K103N/Y181C ВИЧ-1 // Хим.-фармац. ж., 2015. Т. 49, N 10.-С.40-43
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| Effect of mutations at position E138 in HIV-1 reverse transcriptase and their interactions with the M184I mutation on defining patterns of resistance to nonnucleoside reverse transcriptase inhibitors rilpivirine and etravirine // Antimicrob. Agents and Chemother., 2013. Vol. 57, N 7.-С.3100-3109
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20.
| The disposition and metabolism of GW695634: A non-nucleoside reverse transcriptase inhibitor (NNRTi) for treatment of HIV/AIDS // Xenobiotica, 2010. Vol. 40, N 6.-С.437-445
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