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Общее количество найденных документов : 60
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1.
Worboys Philip D. Kinetics of drug metabolism in rat liver slices: Rates of oxidation of ethoxycoumarin and tolbutamide, examples of high- and low-clearance compounds // Drug Metab. and Disposit.: Biol. Fate Chem., 1995. Vol. 23, N 3.-С.393-387

2.
In vivo disposition of caffeine predicted from hepatic microsomal and hepatocyte data // Drug Metab. and Disposit.: Biol. Fate Chem., 1995. Vol. 23, N 3.-С.349-353

3.
In vivo disposition of caffeine predicted from hepatic microsomal and hepatocyte data // Drug Metab. and Disposit.: Biol. Fate Chem., 1995. Vol. 23, N 3.-С.349-353

4.
Comparison of ketoconazole and fluconazole as cytochrome P450 inhibitors: Use of steady-state infusion approach to achieve plasma concentration-response relationships // Drug Metab. and Disposit.: Biol. Fate Chem., 1996. Vol. 24, N 2.-С.211-215

5.
Pharmacokinetics in early drug research: The report and recommendations of ECVAM workshop 22 // ATLA, 1997. Vol. 25, N 1.-С.17-31

6.
Pharmacokinetics in early drug research: The report and recommendations of ECVAM workshop 22 // ATLA, 1997. Vol. 25, N 1.-С.17-31

7.
Worboys Philip D. Kinetics of drug metabolism in rat liver slices II: Comparison of clearance by liver slices and freshly isolated hepatocytes // Drug Metab. and Disposit.: Biol. Fate Chem., 1996. Vol. 24, N 6.-С.676-681

8.
The use of biokinetics and in vitro methods in toxicological risk evaluation: The report and recommendations of ECVAM Workshop 15 // ATLA, 1996. Vol. 24, N 4.-С.473-493

9.
Worth Andrew P. The validation of computational prediction techniques // ATLA, 1998. Vol. 26, N 2.-С.241-247

10.
Influence of slice thickness and culture conditions on the metabholism of 7-ethoxycoumarion in precision-cut rat liver slices // ATLA, 1998. Vol. 26, N 4.-С.541-548

11.
Influence of slice thickness and culture conditions on the metabholism of 7-ethoxycoumarion in precision-cut rat liver slices // ATLA, 1998. Vol. 26, N 4.-С.541-548

12.
Microsomal prediction of in vivo clearance of CYP2C9 substrates in humans // Brit. J. Clin. Pharmacol., 1999. Vol. 47, N 6.-С.625-635

13.
An integrated approach to the prediction of systemic toxicity using biokinetic models and biological in vitro test methods // ATLA, 1999. Vol. 27, Spec. iss..-С.105

14.
An integrated approach to the prediction of systemic toxicity using biokinetic models and biological in vitro test methods // ATLA, 1999. Vol. 27, Spec. iss..-С.105

15.
Bicknell Holly A. Regioselective and stereoselective hydroxylations of warfarin in human liver microsomes and c-DNA expressed cytochrome P450 // Drug Metab. Rev., 2000. Vol. 32, прил. N 1.-С.35

16.
Witherow Lynn E. Sigmoidal kinetics of CYP3A substrates. An approach for scaling dextromethorphan metabolism in hepatic microsomes and isolated hepatocytes to predict in vivo clearance in rat // J. Pharmacol. and Exp. Ther., 1999. Vol. 290, N 1.-С.58-65

17.
Carlile David J. Kinetics of drug metabolism in rat liver slices IV: Comparison of ethoxycoumarin clearance by liver slices, isolated hepatocytes, and hepatic microsomes from rats pretreated with known modifiers of cytochrome P-450 activity // Drug Metab. and Disposit., 1999. Vol. 27, N 4.-С.526-532

18.
Houston J.Brian In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model // Drug Metab. and Disposit., 2000. Vol. 28, N 3.-С.246-254

19.
Rawden Helen C. Prediction of hepatic clearance of the benzodiazepines from human liver microsomes via substrate depletion // Drug Metab. Rev., 2000. Vol. 32, прил. N 1.-С.93

20.
Rawden Helen C. Prediction of hepatic clearance of the benzodiazepines from human liver microsomes via substrate depletion // Drug Metab. Rev., 2000. Vol. 32, прил. N 1.-С.93

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