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Общее количество найденных документов : 16
Показаны документы с 1 по 16
1.
Influence of age and gender on valproic acid glucuronidation in rats // Drug Metab. and Disposit.: Biol. Fate Chem., 1996. Vol. 24, N 3.-С.367-370

2.
Oxidation of epinephrine to adrenochrome by reactive oxygen species and its inhibitory effect on cytochrome P450 activity // Drug Metab. Rev., 2003. Vol. 35, прил. 2.-С.178

3.
P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists // Drug Metab. and Dispos., 2003. Vol. 31, N 3.-С.312-318

4.
Chen The fallacy of using adrenochrome reaction for measurement of reactive oxygen species formed during cytochrome P450-mediated metabolism of xenobiotics // J. Pharmacol. and Exp. Ther., 2002. Vol. 300, N 2.-С.417-420

5.
A high-throughput assay for measuring the metabolic stability of compounds towards CYP3A4 metabolism // Drug Metab. Rev., 2003. Vol. 35, прил. 2.-С.92

6.
Chen The fallacy of using adrenochrome reaction for measurement of reactive oxygen species formed during cytochrome P450-mediated metabolism of xenobiotics // J. Pharmacol. and Exp. Ther., 2002. Vol. 300, N 2.-С.417-420

7.
Impact of MRP2 on the biliary excretion and intestinal absorption of model compounds using EISAI hyperbilirubinemic rats // Drug Metab. Rev., 2002. Vol. 34, прил. 1.-С.84

8.
Chen Utilities of measuring relative unbound fraction in drug discovery and development // Drug Metab. Rev., 2002. Vol. 34, прил. 1.-С.135

9.
Chen P-glycoprotein does not limit significantly the brain penetration of -statins // Drug Metab. Rev., 2003. Vol. 35, прил. 2.-С.152

10.
Differential interaction of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors with ABCB1, ABCC2, and OATP1B1 // Drug Metab. and Dispos., 2005. Vol. 33, N 4.-С.537-546

11.
The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: Evaluation using the MDR1A/1B knockout mouse model // Drug Metab. and Dispos., 2005. Vol. 33, N 1.-С.165-174

12.
P-glycoprotein has differential effects on the disposition of statin acid and lactone forms in mdr1a/b knockout and wild-type mice // Drug Metab. and Dispos., 2007. Vol. 35, N 10.-С.1725-1729

13.
Use of a physiologically based pharmacokinetic model to study the time to reach brain equilibrium: An experimental analysis of the role of blood-brain barrier permeability, plasma protein binding, and brain tissue binding // J. Pharmacol. and Exp. Ther., 2005. Vol. 313, N 3.-С.1254-1262

14.
P-glycoprotein has differential effects on the disposition of statin acid and lactone forms in mdr1a/b knockout and wild-type mice // Drug Metab. and Dispos., 2007. Vol. 35, N 10.-С.1725-1729

15.
Utility of a novel Oatp1b2 knockout mouse model for evaluating the role of Oatp1b2 in the hepatic uptake of model compounds // Drug Metab. and Dispos., 2008. Vol. 36, N 9.-С.1840-1845

16.
Liu Progress in brain penetration evaluation in drug discovery and development // J. Pharmacol. and Exp. Ther., 2008. Vol. 325, N 2.-С.349-356

 




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